Thoracic Aortic Banding Mice

A Expression By A MicroRNA - Harvard University
Expression by a MicroRNA Eva van Rooij,1 Lillian B. Sutherland,1 Xiaoxia Qi,1 James A. Richardson,1,2 response of wild-type and miR-208 mutant mice to thoracic aortic banding (TAB), which induces cardiac hypertrophy by increased afterload on the ... Read Here

Inhibition Of Histone Deacetylase Activity Diminishes ...
TSA subjected to thoracic aortic banding (TAB)-induced pressure stress in mice. In histological observations, TAB in treated mice showed a significant hypertrophic response, (Key words : Histone deacetylase, Thoracic aortic banding, Cardiac hypertrophy, Trichostatin A) INTRODUCTION ... View Doc

Antioxidant Amelioration Of Dilated Cardiomyopathy Caused By ...
Antioxidant Amelioration of Dilated Cardiomyopathy Caused by Conditional Deletion of NEMO/IKK in Cardiomyocytes P. Kratsios, because thoracic aortic banding of young Nemohko mice Mice constitutively lacking NEMO die during embryonic ... Access Document

Journal Of Molecular And Cellular Cardiology
Overload cardiac hypertrophy induced by thoracic aortic banding in neonatal rabbits [21]. In mice, transverse aortic constriction leads to an increase in some nuclear-encoded enzymes of the Krebs cycle and sub-units of complexes I, III, IV, ... View Full Source

Surgical Animal Model Of Ventricular Hypertrophy
Aortic banding markedly reduces survival in mice deficient in 2A-ARs or 2C-ARs and induces a much higher incidence of heart failure along with enhanced LVH and fibrosis and elevated circulating. Thoracic Aortic Banding (see Note 2) 1. ... Fetch Doc

Shawn D. Hingtgen, Zhenbo Li, William Kutschke, Xin Tian, Ram ...
To thoracic aortic banding (TAB) or sham surgery, and intramyocar-dial injections of viral vectors (AdCu/ZnSOD, AdDNAkt, or control) were performed. There was robust transgene expression in the heart, In mice injected with AdBgL II, TAB ... Fetch Full Source

Editorial Commentary - Hyper.ahajournals.org
After aortic banding but were restored by either PD or bradykinin B 2 receptor antagonist icatibant. endothelial NO synthase phosphorylation in thoracic aorta of mice with abdominal aortic banding via type 2 receptor. Hypertension. 2006;48: ... Retrieve Document

MicroRNA-133a Regulates Cardiomyocyte Proliferation And ...
MicroRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart Ning Liu, 1Svetlana Bezprozvannaya, We also performed thoracic aortic banding (TAB) on these mice to test their response to pressure overload and observed no difference in the ... Fetch Document

TRPC6 Fulfills A Calcineurin Signaling Circuit During ...
TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling Thoracic aortic banding. Male mice (6–8 weeks old) either underwent a sham operation or were subjected to pressure overload induced by TAB as ... Retrieve Full Source

CCN2/CTGF Attenuates Myocardial Hypertrophy And Cardiac ...
CCN2/CTGF attenuates myocardial hypertrophy and cardiac dysfunction upon Transgenic mice Heart failure Aortic banding Cardiac hypertrophy CTGF Background: determined by successive trans-thoracic echocardiography Tg-CTGF mice (— —; n=7) and NLC mice (-- --; n=9) ... Access Full Source

Modulation Of Adverse Cardiac Remodeling By STARS, A Mediator ...
Modulation of adverse cardiac remodeling by STARS, a mediator muscle activator of Rho signaling; TAB, thoracic aortic banding. Conflict of interest: aortic banding (TAB) and in hearts of Tg mice expressing consti- ... Read Document

A Dynamic Notch Injury Response Activates Epicardium And ...
A Dynamic Notch Injury Response Activates Epicardium and Contributes to Fibrosis Rationale: Transgenic Notch reporter mice express enhanced green fluorescent protein in cells with C Myocardial infarction and thoracic aortic banding amplified the NEC pool, increasing fibroblast ... Visit Document

Dallas, Texas, USA Author Manuscript NIH Public Access USA ...
Thoracic aortic banding (TAB) The most commonly used surgical intervention to promote pressure overload-induced cardiac hypertrophy in mice is thoracic aortic banding (TAB; also termed thoracic aortic constriction, TAC). ... Return Document

Thoracic Peri-aortic Fibrosis In A Patient Of Psoriasis
THORACIC RADIOLOGY: Thoracic peri-aortic fibrosis in a patient of psoriasis Thoracic peri-aortic fibrosis in a patient of psoriasis reduces left ventricular mass with chronic aortic banding in mice, ... Return Document

RNA Interference As A Resistance Mechanism Against Crop ...
Comparative differential proteomic profiles of nonfailing and failing hearts after in vivo thoracic aortic constriction in mice overexpressing FKBP12.6 ... View Doc

Dissection Of The Murine thoracic Aorta. - YouTube
After cleaning the fur with 70% ethanol, a single cut and blunt dissection are used to expose the rib cage. The thoracic cavity is opened and the heart and lungs removed. The aorta is indicated with white arrowheads in the still image. The aorta is carefully dissected as described in ... View Video

Inhibition Of Endogenous Thioredoxin In The Heart Increases ...
Performed by ligation of the transverse thoracic aorta between the innominate artery and left common carotid artery with a 28-gauge needle using a 7-0 braided poly- aortic banding in Tg-DN-Trx1 mice caused decreases in LVESD due to concentric hypertrophy rather than LV Figure 6 ... Access Doc

Effects Of Anesthesia On Conventional And Speckle Tracking ...
Genetically-modified mice are widely applied in cardiovascular studies as model organisms. The sham (n=15); mild thoracic aortic banding (TAB; n=15); and severe TAB (n=8) groups. ISF was administered under deep anesthesia (DA ; 1-2% ISF), light anesthesia (LA; 0.5-1% ISF) and immediately ... Access Doc